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The clinical value of digital colposcopy in cervical intraepithelial neoplasia

Released on Jul. 20, 2021

Cervical intraepithelial neoplasia (CIN) is a collective term for a group of precancerous lesions closely related to cervical invasive cancer. Including cervical dysplasia and cervical carcinoma in situ, reflecting the continuous development process of cervical cancer, that is, a series of pathology from cervical dysplasia (light→medium→severe)→carcinoma in situ→early invasive carcinoma→invasive carcinoma Variety.

Digital colposcopy has now become one of the important methods for early diagnosis of cervical intraepithelial neoplasia (CIN) and cervical cancer, and it can be followed up after treatment and prospective research.

Advantages of digital colposcopy

Intraepithelial neoplasia may have no obvious symptoms. Gynecological examinations are often characterized by cervical erosion, but no obvious clinical symptoms and cervical smoothness or small erosion range. Patients with cytology in the normal range are easily missed clinically. The colposcopy magnifies the observation site by 6-40 times. Its high-quality light source and high-magnification images can observe the fine structure of the lesion, and can find abnormal epithelium, blood vessels, and suspicious lesions that are difficult to detect with the naked eye, and can be determined in a targeted manner The biopsy site improves the accuracy of biopsy.

Digital colposcopy method

Patients should avoid vaginal examination, douche and sex life, and vaginal cleanliness of 1 to 2 degrees during non-menstrual periods 24 hours before the examination. Expose the cervix, wipe off the secretions, observe the surface of the cervix with a 10x low-degree microscope under white light, rub the cervix with 4% acetic acid for 1 minute, observe the squamous columnar epithelium and transformation area, look for abnormal colposcopy images, and use it when observing blood vessels Green and green lenses, followed by a compound iodine solution, take a biopsy in the negative area of the iodine test or the suspicious lesion, and send it for pathological examination.

Limitations of digital colposcopy

Digital colposcopy is often limited by the experience and technical level of itself and the examiner. Colposcopy is an examination under direct vision. It cannot detect the lesions in the cervical canal. There are often false negatives. Even with the help of a cervical canal dilator, it is difficult to observe the lesions in the cervical canal as comprehensively as the surface of the cervix. Therefore, it is recommended before local cervical treatment. Be sure to perform cytology, colposcopy and other examinations to rule out cervical cancer. If necessary, perform cervical curettage or conization and make an early diagnosis.